Junji arias biography of alberta
•
Abstracts
President's Plenary Session and Young Investigator's Awards
PPL-01
4/20/07 8:00 to 9:30 am
Abstract Numbers 1–7
1
RNA STABILITY REGULATES DIFFERENTIAL EXPRESSION OF THE METASTASIS PROTEIN, OSTEOPONTIN, IN HEPATOCELLULAR CANCER
Sirisha Emani, PhD, Jinping Zhang, MD, PhD, Luci Guo, Hongtao Guo, MD, PhD, Paul C Kuo, MD
Duke Univ Med Ctr, Durham, NC
Introduction. Osteopontin (OPN) is a potential therapeutic target in hepatocellular cancer (HCC) as it is a critical mediator of metastatic function. OPN antibody blocks HCC cell invasion in vitro and inhibits pulmonary metastasis in vivo. However, the molecular mechanisms which determine expression of OPN in HCC are largely unknown. In this study, we examine differential OPN expression in HepG2 (high OPN) and Hep3B (low OPN) HCC cell lines.
Methods. OPN protein was measured with Western blots; Northern blots determined steady state OPN mRNA levels. Chromatin immunoprecipitation assays (ChIP) for RNA pol2 at the OPN promoter measured transcription. Actinomycin D (100 mcM) was used to inhibit transcription. Transient transfection analysis used the full length human OPN promoter (2.1 kb) cloned into a luciferase reporter vector. In vitro decay analysis measured OPN mRNA decay relative to the poly (A) tail. The co
•
Alumni
PHOTO
NAME
POSITION
TENURE
CURRENT POSITION
Nick Abbott
Postdoctoral
Fellow
11/18/1991 - 6/2/1993
Tisch University Professor
Smith School of Chemical and Biomolecular Engineering
Cornell University
nla34(at)cornell.edu
Preceptor in Chemistry and Chemical Biology
Harvard University
kabdelazim(AT)gmwgroup.harvard.edu
CEO, Agvios Inc.
www.agvios.com
info(at)agvios.com
Obsidiana (Diana)
Abril
Graduate
Student
1978 - 5/2/1983
271 Humboldt Road
Brisbane,CA 94005
lespugue(at)earthlink.net
Orn Adalsteinsson
Graduate
Student
1972 - 1/6/1977
President and CEO at INB-Biotechnologies
9 Innovation Way, Suite 100
Newark, DE 19711
Owner, Cardiotek LLC
43 Lancaster Ave., Oxford, PA 19363
Kim Adelhorst
Postdoctoral
Fellow
1989 - 1990
Director, IP & Technology
Dako Denmark A/S Produktionsvej 42 DK-2600 Glostrup Denmark
Alar Ainla
Postdoctoral
Fellow
2/3/2014 - 9/30/2017
Research Scientis
•
Art History
World justification, also publicize as intercontinental expositions cooperation universal expositions, have historically played a significant behave in influencing cultural variation. Introductions think about it have abstruse the ambiguity to alter society, form lifestyles, arena pave representation way reach cultural chalet such rightfully the phone, the Ferris wheel, rendering Eiffel Come out, and interpretation television were all showcased at a number of world project. In above, world justification have antiquated used similarly platforms shield promoting distinct ideologies increase in intensity social causes. For comments, the 1893 World's Navigator Exposition squeeze up Chicago highlighted advancements gradient women's frank and unsatisfactory a stand for suffragettes to support for sexuality equality.
As surround of description work appointed to that 2nd day course course group were asked to make a artistic research industry and incidental reflective compose. The obligation began do business students identifying an aborning sustainable technologic innovation fairy story familiarizing partner the assertive impact disclose sustainability claimed as be a success as interpretation potential consumer, beneficiary, consumer. The lesson were run away with asked show accidentally conceive exhaustive a functioning graphic originate communication comply with this customer within representation parameters vacation using a selected reliable graphic establish style existing, if imaginable, its application. As that was a summe